General Information

  • ID:  hor001188
  • Uniprot ID:  A8Y215
  • Protein name:  FLP-9
  • Gene name:  flp-9
  • Organism:  Caenorhabditis briggsae
  • Family:  FMRFamide related peptide family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Caenorhabditis (genus), Peloderinae (subfamily), Rhabditidae (family), Rhabditoidea (superfamily), Rhabditomorpha (infraorder), Rhabditina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  GO:0071855 neuropeptide receptor binding
  • GO BP:  GO:0001508 action potential; GO:0007218 neuropeptide signaling pathway; GO:0007626 locomotory behavior
  • GO CC:  GO:0005576 extracellular region

Sequence Information

  • Sequence:  KPSFVRF
  • Length:  7
  • Propeptide:  MSRLYALLLIVCIANVASTAPESIPDLDALAEFCAKESNKRYCAQLAQLSLDSAMEANQEQVIQMEKRKPSFVRFGKRSGYPLIIDNEELRMDKRKPSFVRFGRK
  • Signal peptide:  MSRLYALLLIVCIANVAST
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-A8Y215-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor001188_AF2.pdbhor001188_ESM.pdb

Physical Information

Mass: 98724 Formula: C43H65N11O9
Absent amino acids: ACDEGHILMNQTWY Common amino acids: F
pI: 11.65 Basic residues: 2
Polar residues: 1 Hydrophobic residues: 3
Hydrophobicity: -14.29 Boman Index: -1387
Half-Life: 1.3 hour Half-Life Yeast: 3 min
Half-Life E.Coli: 2 min Aliphatic Index 41.43
Instability Index: 2531.43 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  18760316
  • Title:  Comparative Peptidomics of Caenorhabditis Elegans Versus C. Briggsae by LC-MALDI-TOF MS